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XU Zhongming, HUANG Ping
《机械工程前沿(英文)》 2007年 第2卷 第4期 页码 474-477 doi: 10.1007/s11465-007-0082-y
关键词: coefficient dissipation mechanism universal adhesive interfacial Independent Oscillator
On the applicability of different adhesion models in adhesive particulate flows
Guanqing LIU, Shuiqing LI, Qiang YAO,
《能源前沿(英文)》 2010年 第4卷 第2期 页码 280-286 doi: 10.1007/s11708-009-0062-5
关键词: adhesive contact van der Waals force adhesion model adhesion map DEM
null
《医学前沿(英文)》 2017年 第11卷 第4期 页码 471-479 doi: 10.1007/s11684-017-0602-z
Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutinin stalk domain are in development. Typically, these vaccines induce responses that target group 1 or group 2 hemagglutinins with little to no cross-group reactivity and protection. Similarly, the majority of human anti-stalk monoclonal antibodies that have been isolated are directed against group 1 or group 2 hemagglutinins with very few that bind to hemagglutinins of both groups. Here we review what is known about the human humoral immune response to vaccination and infection with H7 subtype influenza viruses on a polyclonal and monoclonal level. It seems that unlike vaccination with H5 hemagglutinin, which induces antibody responses mostly restricted to the group 1 stalk domain, H7 exposure induces both group 2 and cross-group antibody responses. A better understanding of this phenomenon and the underlying mechanisms might help to develop future universal influenza virus vaccine candidates.
关键词: universal influenza virus vaccine hemagglutinin stalk H7N9
Severe adhesive small bowel obstruction
null
《医学前沿(英文)》 2012年 第6卷 第4期 页码 436-439 doi: 10.1007/s11684-012-0221-7
Adhesive small bowel obstruction is a frequent cause of hospital admission. Water soluble contrast studies may have diagnostic and therapeutic value and avoid challenging demanding surgical operations, but if bowel ischemia is suspected, prompt surgical intervention is mandatory. A 58-year-old patient was operated for extensive adhesive small bowel obstruction after having had two previous laparotomies for colorectal surgery, and had a complex clinical course with multiple operations and several complications. Different strategies of management have been adopted, including non-operative management with the use of hyperosmolar water soluble contrast medium, multiple surgical procedures, total parenteral nutrition (TPN) support, and finally use of anti-adherences icodextrin solution. After 2 years follow-up the patient was doing well without presenting recurrent episodes of adhesive small bowel obstruction. For patients admitted several times for adhesive small bowel obstruction, the relative risk of recurring obstruction increases in relation to the number of prior episodes. Several strategies for non-operative conservative management of adhesive small bowel obstruction have already addressed diagnostic and therapeutic value of hyperosmolar water soluble contrast. According to the most recent evidence-based guidelines, open surgery is the preferred method for surgical treatment of strangulating adhesive small bowel obstruction as well as after failed conservative management. Research interest and clinical evidence are increasing in adhesions prevention. Hyaluronic acid-carboxycellulose membrane and icodextrin may reduce incidence of adhesions.
关键词: post-operative intraperitoneal adhesions adhesive small bowel obstruction adhesiolysis antiadhesion treatments hyperosmolar water soluble contrast medium
Learning from biological attachment devices: applications of bioinspired reversible adhesive methods
《机械工程前沿(英文)》 2022年 第17卷 第3期 doi: 10.1007/s11465-022-0699-x
关键词: adhesion bioinspired attachment biomimetic gripper climbing robot
Parasitic rotation evaluation and avoidance of 3-UPU parallel mechanism
Haibo QU, Yuefa FANG, Sheng GUO
《机械工程前沿(英文)》 2012年 第7卷 第2期 页码 210-218 doi: 10.1007/s11465-012-0317-4
Based on the prototype of 3-UPU (universal-prismatic-universal joint) parallel mechanism proposed by Tsai [ ], the parasitic rotation evaluation is performed and calculated the bound of instability of SNU Seoul National University 3-UPU parallel mechanism. Through analysis of the terminal constraint system of the 3-UPU parallel mechanism, the equation about the parasitic rotation and limited clearance is presented. Then the norm of possible parasitic rotation is employed to evaluate the mechanism stability with limited clearance. The higher this number the worst is the pose, the lower it is the best it is. And the contour atlas of parasitic rotation is obtained, which can be used for further analysis and design. With the practice experiment result of SUN 3-UPU parallel mechanism, we find it’s bound of instability, which indicates there will appear the parasitic rotation when the number exceeds the bound. Finally, the method for avoidance of possible parasitic motions is presented by adding redundantly actuated limbs.
关键词: parallel mechanism 3-UPU (universal-prismatic-universal joint) parasitic motions limited clearance redundantly actuated limbs
Design of a novel RTD-based three-variable universal logic gate
Mao-qun YAO,Kai YANG,Cong-yuan XU,Ji-zhong SHEN
《信息与电子工程前沿(英文)》 2015年 第16卷 第8期 页码 694-699 doi: 10.1631/FITEE.1500102
关键词: Resonant tunneling diode (RTD) Threshold logic gate Reed-Muller expansion Universal logic gate
Tuning the electronic structure of NiCoP arrays through V doping for pH-universal hydrogen evolution
Yu Lin, Jinlei Wang, Duanlin Cao, Yaqiong Gong
《化学科学与工程前沿(英文)》 2021年 第15卷 第5期 页码 1134-1146 doi: 10.1007/s11705-020-2014-x
关键词: hydrogen evolution reaction transition metal phosphides pH-universal vanadium doping carbon fiber paper
Shoshan T. Abrahami, John M. M. de Kok, Herman Terryn, Johannes M. C. Mol
《化学科学与工程前沿(英文)》 2017年 第11卷 第3期 页码 465-482 doi: 10.1007/s11705-017-1641-3
关键词: aluminum Cr(VI)-free surface pre-treatments anodizing adhesive bonding
Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying
《医学前沿(英文)》 2020年 第14卷 第2期 页码 149-159 doi: 10.1007/s11684-020-0764-y
关键词: influenza virus neutralizing antibody hemagglutinin globular head region trimeric interface
Shen LIU, Shengzhe SHANG, Xuezhen YANG, Huihua ZHANG, Dan LU, Ning LI
《农业科学与工程前沿(英文)》 2018年 第5卷 第3期 页码 382-389 doi: 10.15302/J-FASE-2018211
The mammary gland provides a novel method for producing recombinant proteins in milk of transgenic animals. A key component in the technology is the construction of an efficient milk expression vector. Here, we established a simple method to construct a milk expression vector, by a combination of homologous recombination and digestion-ligation. Our methodology is expected to have the advantages of both plasmid and bacterial artificial chromosome (BAC) vectors. The BAC of mouse whey acidic protein gene (mWAP) was modified twice by homologous recombination to produce a universal expression vector, and the human lysozyme gene (hLZ) was then inserted into the vector by a digestion-ligation method. The final vector containing the 8.5 kb mWAP 5′ promoter, 4.8 kb hLZ genomic DNA, and 8.0 kb mWAP 3′ genomic DNA was microinjected into pronuclei of fertilized mouse embryos, to successfully generate two transgenic mouse lines that expressed recombinant human lysozyme (rhLZ) in milk. The highest expression level of rhLZ was 0.45 g·L−1, and rhLZ exhibited the same antibacterial activity as native hLZ. Our results have provided a simple approach to construct a universal milk expression vector, and demonstrated that the resulting vector regulates the expression of hLZ in milk.
关键词: BAC recombinant methods gene expression human lysozyme transgenic mice milk expression vector
用于实时皮肤创面愈合的超强工程化蛋白凝聚体黏合剂 Article
李铭, 柳柏梅, 徐炜, 赵来, 王自立, 何浩男, 李敬敬, 王帆, 马超, 刘凯, 张洪杰
《工程(英文)》 2023年 第31卷 第12期 页码 76-85 doi: 10.1016/j.eng.2023.07.013
黏合剂作为生物医学工程中的一种先进方式,因其独特的伤口管理行为而备受关注。然而,由于当前的黏合剂系统界面粘合强度较弱,要实现牢固的黏合仍是一项巨大的挑战。此外,传统化学黏合剂缺乏动态适应性,限制了伤口周围的新生细胞向该部分迁移,导致组织再生效果不佳。在此,我们精心设计了一种具有强大黏附力和实时促皮肤愈合效果的细胞外基质衍生的生物复合黏合剂。在嵌合蛋白和天然DNA间超分子相互作用的积极参与下,液-液相分离被很好地用来驱动生物复合黏合剂的组装,从而获得增强的黏合性能。该生物黏合剂具有出色的黏合和止血性能,其中,剪切黏合强度约18 MPa,优于已报道的同类产品。此外,工程生物衍生成分赋予了该黏合材料优异的生物相容性和特殊的生物学功能,包括促进细胞增殖和迁移,因此使用这种材料最终可实现实时原位皮肤再生。这项工作为功能化生物黏合剂工程和生物医学转化开辟了新的途径。
基于RTD三变量通用逻辑门的函数综合算法 Article
Mao-qun YAO, Kai YANG, Ji-zhong SHEN, Cong-yuan XU
《信息与电子工程前沿(英文)》 2017年 第18卷 第10期 页码 1654-1664 doi: 10.1631/FITEE.1601730
Eugene Averin
《工程(英文)》 2017年 第3卷 第6期 页码 888-891 doi: 10.1016/j.eng.2017.12.004
Patterned wafer bonding using ultraviolet adhesive
Rui ZHUO, Guanglan LIAO, Wenliang LIU, Lei NIE, Tielin SHI
《机械工程前沿(英文)》 2011年 第6卷 第2期 页码 214-218 doi: 10.1007/s11465-011-0130-5
The process of patterned wafer bonding using ultraviolet (UV) adhesive as the intermediate layer was studied. By presetting the UV adhesive guide-layer, controlling the thickness of the intermediate layer (1– 1.5 μm), appropriate pre-drying temperature (60°C), and predrying time (6 min), we obtained the intermediate layer bonding of patterned quartz/quartz. Experimental results indicate that patterned wafer bonding using UV adhesive is achieved under room temperature. The process also has advantages of easy operation, low cost, and no plugging or leakage in the patterned area after bonding. Using the process, a microfluidic chip for red blood cell counting was designed and fabricated. Patterned wafer bonding using UV adhesive will have great potential in the fabrication of microfluidic chips.
关键词: ultraviolet (UV) adhesive intermediate layer patterned wafer bonding
标题 作者 时间 类型 操作
Calculating frictional force with considering material microstructure and potential on contact surfaces
XU Zhongming, HUANG Ping
期刊论文
On the applicability of different adhesion models in adhesive particulate flows
Guanqing LIU, Shuiqing LI, Qiang YAO,
期刊论文
Universal influenza virus vaccines: what can we learn from the human immune response following exposure
null
期刊论文
Learning from biological attachment devices: applications of bioinspired reversible adhesive methods
期刊论文
Parasitic rotation evaluation and avoidance of 3-UPU parallel mechanism
Haibo QU, Yuefa FANG, Sheng GUO
期刊论文
Design of a novel RTD-based three-variable universal logic gate
Mao-qun YAO,Kai YANG,Cong-yuan XU,Ji-zhong SHEN
期刊论文
Tuning the electronic structure of NiCoP arrays through V doping for pH-universal hydrogen evolution
Yu Lin, Jinlei Wang, Duanlin Cao, Yaqiong Gong
期刊论文
Towards Cr(VI)-free anodization of aluminum alloys for aerospace adhesive bonding applications: A review
Shoshan T. Abrahami, John M. M. de Kok, Herman Terryn, Johannes M. C. Mol
期刊论文
Recent advances in “universal” influenza virus antibodies: the rise of a hidden trimeric interface in
Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying
期刊论文
Construction of a universal recombinant expression vector that regulates the expression of human lysozyme
Shen LIU, Shengzhe SHANG, Xuezhen YANG, Huihua ZHANG, Dan LU, Ning LI
期刊论文